Cannabis And Parkinson's Disease - Medpage Today now in New Zealand

Published Jun 23, 22
6 min read

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As mentioned previously, many people with Parkinson’s disease go on to develop Parkinson’s disease dementia. Persons with PD and PDD often seek treatment in the form of prescription medications to alleviate the symptoms, frequently with adverse side effects including dizziness, drowsiness, blurred vision, nausea, diarrhea, vomiting, dry mouth, loss of appetite, heartburn, and more.

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A recently published study from Brazilian researchers showed that CBD reduced anxiety and tremors that occurred during a public speaking test for people over 60 with PD. Subjects who took 300 milligrams of CBD before giving a speech (public speaking is a classic anxiety-inducer) had less symptoms than a control group who were given a placebo.



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Because PD affects the brain’s ability to produce dopamine, researchers Alyssa S. Laun and Zhao-Hui Song from the University of Louisville, Kentucky, made an important discovery a few years ago when they found that CBD acts as an “inverse agonist” on CPR6 receptors found predominantly in the basal ganglia region of the brain, which connects to the cerebral cortex and brainstem, driving functions in our bodies including movement, learning, and emotion.

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Any increase in dopamine levels would counteract the steady decrease of dopaminergic neurons experienced by those afflicted with PD. Cannabinoid receptors run throughout our body as part of the endocannabinoid system regulating physiological operations including hunger, pain sensitivity, temperament, and memory. These natural receptors are affected in patients with PD.

CBD may also reduce depression and anxiety, and relieve pain. A study at the Colorado School of Medicine has demonstrated relief of issues including tremors and difficulty sleeping. CBD studies are also showing it as effective in treating the psychosis that comes with PDD (Parkinson’s disease dementia). So far, patients are tolerant of low doses of CBD oil and report positive effects.

government patent on cannabinoids as antioxidants and neuroprotectants. Further, THC and CBD products are becoming mainstream as an increasing number of states legalize cannabis for medicinal and even recreational purposes. (For more on legalized CBD, see below.) According to the Parkinson’s Foundation, roughly 60,000 Americans are diagnosed with Parkinson’s annually, and more than 10 million people worldwide live with PD. Mobile Hydraulic hose near me Newcastle.

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While there are currently no CBD medications approved by the FDA specifically for Parkinson’s disease, one should not be discouraged, as research is ongoing. In 2017, the Salk University in California found that THC and other compounds found in cannabis, such as CBD, reduce the amount of amyloid beta, a plaque protein that is toxic in the brains of persons with Alzheimer’s disease.

The above-mentioned study also showed that the use of medicinal marijuana (which contains both THC and CBD) helped patients manage their pain better, whereas studies conducted on animals indicate that CBD treatment alone, due to its anti-inflammatory properties, can reduce pain and inflammation. Hydraulic hose replacement Newcastle. CBD Oil for Parkinson’s Hallucinations and Psychosis It is estimated that around a third of patients with Parkinson’s also experience psychosis, most commonly hallucinations and delusions.

In a small 2009 study, 6 PD patients, suffering from psychosis for at least 3 months, were given an oral dose of CBD for 4 weeks. The results from this research on CBD and Parkinson’s on the NIH website showed a considerable decrease in psychotic symptoms. What’s more, the study didn’t find any adverse effects from CBD use on motor functions or negative effects on general well-being and health.

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Hopefully, this research, and others like it, will help generate more interest and encourage more studies into the benefits of CBD oil for Parkinson’s. Living with Parkinson’s isn’t easy. This disease, which only gets worse with time, can seriously jeopardize a person’s ability to lead a normal life. Luckily, studies show that CBD treatment can offer some relief.

Another study on CBD oil and Parkinson’s that included 119 patients also pointed out that CBD plays a significant role in the patients’ well-being and their quality of life (24 hour On-site Hydraulic hose near me Newcastle). In this study, participants were given a placebo and CBD (either 75 mg/day or 300 mg/day) and although motor and general symptoms did not improve, findings showed a higher quality of life scores.

How to Administer CBD Oil for Parkinson’s Disease? There are several ways that one can take CBD: CBD oils and tinctures — These liquids can be used sublingually (a few drops are placed under the tongue and absorbed quickly into the bloodstream), or they can be added to food or beverages (Emergency Hydraulic hose repair Newcastle).

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Capsules and pills — This form of CBD administration is especially helpful to PD patients who cannot properly dose liquids as a result of tremors - Mobile Hydraulic hose repair Newcastle. The effect when taking CBD oil for Parkinson’s with pills and capsules is a bit delayed, but once it kicks in, it can be felt for 4 hours or longer.

Smoking cannabis — Cannabis can be smoked, vaped or inhaled, though experts advise PD patients to avoid smoking as it may cause damage to the lungs or throat. How much and how often can you take CBD oil? Don’t start with too much too soon. When it comes to PD (and other diseases too), it’s best to start with low doses and work your way up if necessary.

On the other hand, if they believe that their CBD dosage for Parkinson’s is too much, the dosage can be decreased. Some studies indicate that 150 mg over the course of four weeks alleviates psychotic symptoms, while 75 to 300 mg of CBD oil improves REM sleep disorders, albeit the dosage may vary according to body weight and method of consumption.

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Which CBD Oil Is Best For Parkinson’s Disease? Getting the best CBD oil for your condition depends on many factors, and the only way you can make sure that you buy a high-quality product is to shop smart: Read the label. Carefully check how much CBD (and what kind: isolate, full-spectrum, or broad-spectrum) and THC the product contains.